Assessment Of The Impact Of Alcohol Intake On Cognition – A Cohort Study

Alcoho; and cognition

Authors

  • Deekshitha Alla Andhra Medical College

Keywords:

alcohol, Cognition, MoCA

Abstract

BACKGROUND: Alcohol is one of the most consumed psychoactive substances in the world. The deleterious impact of alcoholism is a major public health issue worldwide due to its consequential long-term, social and economic damage. Besides these socioeconomic effects, alcoholism also results in various degrees of physiological aberrations that lead to abnormalities in cognitive and behavioral functions. In India, it is estimated that approximately 75 million people consume alcohol. Evaluation of the impact of alcohol consumption on cognition becomes the need of the hour due to the interference of cognitive decline with daily function and independence.

AIMS: To evaluate cognition ability in alcoholics with a prolonged history of alcohol intake using blinded Montreal Cognitive Assessment (MoCA) and to compare cognition between alcoholics and non-alcoholics.

METHODS: The study includes 30 alcoholic males without any comorbidities (experiment), attending the outpatient department and 30 healthy appropriate non-alcoholics (control) within the age group of 18-45 years of age. Assessment of alcohol intake is done using Alcohol Use Disorder Identification Test (AUDIT) questionnaire and cognitive assessment was performed using blinded Montreal Cognitive Assessment (MoCA) to make it feasible for illiterates. The data was collected and entered into MS-EXCEL sheet and independent sample t test was applied for tests of statistical significance (p-value < 0.001 will be considered as significant). RESULTS: The mean age of the subjects in the experimental group is 40.5±8.5 yrs and that of control group is 39.6±9.82 yrs. In the study, 23.3% were light drinkers, 40% were moderate and 36.6% were light drinkers. The study has shown statistically significant correlation between experimental (12.5±3.95) and control (18.9±2.71) groups.  (p<0.001). Our results included a crucial finding that alcohol consumption has significant impact on cognitive decline.

CONCLUSION: Based on the results of this study, it can be concluded that long-term alcohol consumption has a detrimental influence on cognition. Studies of the cognitive repercussions of alcohol ingesting with the aid of using the usage of the actual international countrywide represented database are scarce within the literature. Higher information on the variations within the effect of alcohol use on cognitive impairment in older adults may also offer precious facts on their care. Conflicting results among various studies could be because of differences in tools used to evaluate cognitive dysfunction; the definitions of the quantity and pattern of alcohol drinking, smoking status, educational and occupational attainment, comorbidities, and psychotropic drug use.

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References

Silva JBS, Cristino ED, Almeida NLd, Medeiros PCBd, Santos NAd (2017) Effects of acute alcohol ingestion on eye movements and cognition: A double-blind, placebo-controlled study. PLoS ONE 12(10): e0186061.

Bartholow BD, Pearson M, Sher KJ, Wieman LC, Fabiani M, Gratton G. Effects of alcohol consumption and alcohol susceptibility on cognition: a psychophysiological examination. Biol Psychol. 2003 Oct;64(1-2):167-90.

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Published

2025-01-01

How to Cite

Alla, D. (2025). Assessment Of The Impact Of Alcohol Intake On Cognition – A Cohort Study: Alcoho; and cognition. International Journal of Medical Students, 12, S347. Retrieved from https://ijms.pitt.edu/IJMS/article/view/2954

Issue

Vol 12. (2024): Supplement 1

Section

Abstracts of the WCMSR

Categories

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Copyright (c) 2024 Deekshitha Alla

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