Moersch-Woltman Syndrome - An Uncommon Conundrum
Keywords:
Anti-GAD Antibodies, Moersch-Woltman Syndrome, Stiff-Person Syndrome, TreatmentAbstract
Recently, this Journal published an interesting case study about the Moersch-Woltman syndrome that affected a middle-aged female, who had not an early diagnosis of this uncommon condition and was longtime submitted to polypharmacy without any improvement of the relentless course of this disease. The authors commented on the importance of a high index of suspicion to get an early correct diagnosis and prompt effective management that is indispensable to result in the best outcomes. The additional short comments on novel literature data aim to emphasize the exemplifying role of reported cases, mainly by enhancing the awareness of non-specialists and primary healthcare workers.
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References
Pitliya A. A Rare Case Report of Neurological Condition: Moersch-Woltman Syndrome with Positive Anti-GAD Antibodies. Int J Med Stud. 2023;11(3):233-6.
Chia NH, McKeon A, Dalakas MC, Flanagan EP, Bower JH, Klassen BT, et al. Stiff person spectrum disorder diagnosis, misdiagnosis, and suggested diagnostic criteria. Ann Clin Transl Neurol. 2023;10(7):1083-94.
Kamaleshwaran KK, Ramkumar E, Senthilkumar E. F-18 Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography Muscle Uptake in Antiglutamic Acid Decarboxylase Antibody-positive Stiff-Person Syndrome. Indian J Nucl Med. 2023;38(2):162-4.
Matsui N, Tanaka K, Ishida M, Yamamoto Y, Matsubara Y, Saika R, et al. Prevalence, Clinical Profiles, and Prognosis of Stiff-Person Syndrome in a Japanese Nationwide Survey. Neurol Neuroimmunol Neuroinflamm. 2023;10(6):e200165.
Perri M, Pellegrini D, Uribe Roca C, Gonzalez F, Buero A, Chimondeguy D, et al. Síndrome de la persona rígida asociado a timoma. Medicina (B Aires). 2023;83(4):626-30.
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