Down Syndrome and Quality of Life: A Case Report
Keywords:Down Syndrome, Alzheimer Disease, Early Onset, Heart Defects, Congenital, Quality of Life
Background: Quality of life is considered a crucial component to the well-being of patients with Down syndrome. The strength of quality care through stable social and psychological interactions has built a framework for a positive well-being for patients with Down syndrome, improving their quality of life.
Case: A 55-year-old African American female with a history of Down syndrome, congenital heart disease, and newly-diagnosed early onset Alzheimer’s disease presented with an arm contusion resulting from regular caretaking. The patient’s history was reviewed, and the complexity of her condition was discovered. While a subset of Down syndrome patients have cardiac complications and others have early-onset Alzheimer’s, our patient had both. We believe this complicated her condition. After the diagnosis of Alzheimer’s was made, the caregivers noticed a significant decline in her ability to communicate and continue day-to-day activities. Despite the decline in functions, a positive mood was apparent.
Conclusion: Multiple medical interventions, along with strong family support, positively contributed to the patient’s quality of life. Therapies targeting cognition could result in the maintenance of quality of life and, ultimately, lower health care costs.
2. Felce D, Perry J. Quality of life: the scope of the term and its breadth of measurement. In: Brown RI, editor. Quality of life for people with disabilities: models, research and practice. Cheltenham (UK): Stanley Thornes; 1997. p. 56-71.
3. Raphael D. Quality of life of persons with developmental disabilities: five issues concerning its nature and measurement. J Dev Disabil. 1997;5(2):44-66.
4. Glasson EJ, Sullivan SG, Hussain R, Petterson BA, Montgomery PD, Bittles
AH. The changing survival profile of people with Down’s syndrome: implica¬tions for genetic counseling. Clin Genet. 2002 Nov;62(5):390-3.
5. Smith DS. Health care management of adults with Down syndrome. Am Fam Physician. 2001 Sep 15;64(6):1031-9.
6. Brown RI. Personal Reflections: quality of life research and Down syndro¬me. Int J Disabil Dev Educ. 1998;45(3):323-9.
7. Brown RI, Brown PM, Bayer MB. A quality of life model: new challenges arising from a six-year study. In: Goode D, editor. Quality of life for persons with disabilities: international perspectives and issues. Cambridge (MA): Brookline Books; 1994. p. 39-56.
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