Case Report: Pulmonary Epithelioid Hemangioendothelioma Presenting as a Solitary Pulmonary Nodule

Authors

Keywords:

Epithelioid Hemangioendothelioma, Lung Neoplasms, Vascular Neoplasms, Thoracic Surgery, Neoplasm Recurrence

Abstract

Background: Pulmonary epithelioid hemangioendothelioma is a rare, highly vascularized tumor with variable clinical presentation including recurrence and metastases. The treatment is complicated by the lack of standardized guidelines along with differing responses to trialed treatments, leaving patients' prognosis unpredictable.

Case: We report a case of a 77-year-old man in whom a left, lower-lobe pulmonary nodule was incidentally discovered during pre-coronary artery bypass graft evaluation. Histopathology confirmed epithelioid hemangioendothelioma. A year later, a recurrence with a right lower-lobe lesion and numerous scattered lesions was identified and resected, confirming metastatic/recurrent epithelioid hemangioendothelioma.

Conclusion: This case emphasizes the importance of long-term surveillance in pulmonary epithelioid hemangioendothelioma due to the potential for delayed recurrence as well as the need for more research to investigate a standardized, yet customizable, approach for better patient outcomes.

References

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Published

2026-07-27

How to Cite

Crew, L., Mott, B., & Chiaffarano , J. (2026). Case Report: Pulmonary Epithelioid Hemangioendothelioma Presenting as a Solitary Pulmonary Nodule. International Journal of Medical Students. Retrieved from https://ijms.pitt.edu/IJMS/article/view/4334

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Copyright (c) 2026 Lilia Crew, Brian Mott, Jeanine Chiaffarano

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